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Is methotrexate an effective and safe treatment for maintaining hair regrowth in people with alopecia totalis? A critically appraised topic.
This article is protected by copyright. All rights reserved. PMID: 29777625 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - May 19, 2018 Category: Dermatology Authors: Browne R, Stewart L, Williams HC Tags: Br J Dermatol Source Type: research

Association of Vitiligo and Alopecia Areata With Atopic Dermatitis A Systematic Review and Meta-analysis
ImportancePrevious studies found conflicting results as to whether atopic dermatitis (AD) is increased in patients with vitiligo and alopecia areata (AA).ObjectiveTo compare the prevalence of AD between patients with either vitiligo or AA and those without these disorders by performing a meta-analysis of observational studies.Data SourcesMEDLINE, EMBASE, Cochrane Library, Google Scholar, and a manual search of 12 additional journals between 1946 and April 5, 2014.Study SelectionObservational studies published in any language that compared the prevalence of AD among patients with and without either vitiligo or AA.Data Extra...
Source: JAMA Dermatology - December 3, 2014 Category: Dermatology Source Type: research

Validation of case identification for alopecia areata using international classification of diseases coding
Conclusions: Patients whose medical records contain an AA-associated ICD code have a high probability of having the condition.
Source: International Journal of Trichology - November 3, 2020 Category: Dermatology Source Type: research

Secondary alopecia induced by aesthetic procedures: An unrecognized potential complication
Australas J Dermatol. 2023 Jun 2. doi: 10.1111/ajd.14090. Online ahead of print.ABSTRACTSurgical facelifts and noninvasive techniques such as mesotherapy, hyaluronic fillers and botulinum toxin, among other procedures are widely used nowadays to reverse skin ageing and achieve rejuvenation effects. Secondary alopecia due to cosmetic procedures is a rare side effect and is poorly described in the literature. The mechanisms in which hair loss develops after an aesthetical procedure or surgical technique are not well known. The development of secondary scarring alopecia or non-scarring alopecia depends upon the interaction be...
Source: The Australasian Journal of Dermatology - June 2, 2023 Category: Dermatology Authors: Carlos A Barrera-Ochoa Mar ía Teresa Alonso-León Roberto Arenas Maria Elisa Vega-Memjie Daniel Asz-Sigall Source Type: research

Diagnosis and Management of Alopecia in Children
Alopecia in childhood is a source of high concern, frustration, and anxiety. Delineating types of alopecia and those that are chronic or potentially related to underlying medical problems is important. There are 5 common types of hair loss in children: alopecia related to tinea capitis, alopecia areata spectrum/autoimmune alopecia, traction alopecia, telogen effluvium, and trichotillomania/trichotillosis. Hair-cycle anomalies including loose anagen syndrome can lead to sparse-appearing hair. Rarer reasons for alopecia in children include pressure-induced alopecia, alopecia related to nutritional deficiency or toxic ingesti...
Source: Pediatric Clinics of North America - January 22, 2014 Category: Pediatrics Authors: Leslie Castelo-Soccio Source Type: research

Ocular findings in patients with alopecia areata
ConclusionsPatients with alopecia may have more lenticular and retinal findings than normal individuals, but those findings do not interfere with visual acuity. Close surveillance for the early onset of cataract formation is important in patients with alopecia.
Source: International Journal of Dermatology - April 6, 2016 Category: Dermatology Authors: Oktay Esmer, Remzi Karadag, Ozgur Cakici, Serap Gunes Bilgili, Yuhanize Tas Demircan, Huseyin Bayramlar, Ayse S. Karadag Tags: Report Source Type: research

Reflectance confocal microscopy for scarring and non-scarring alopecia real-time assessment
In this study, data on reflectance confocal microscopy features useful for the differential diagnosis between scarring and non-scarring alopecia have been identified. Further studies focusing on the use of this non-invasive technique in the therapeutic follow-up and distinction of sub-entities of alopecia are still required.
Source: Archives of Dermatological Research - May 24, 2016 Category: Dermatology Source Type: research

Frictional alopecia of the distal legs: case series and review. Zhao, Johnny; Cohen, Philip R
ConclusionThe incidence of acquired frictional alopecia of the lower extremities may be greater than reflected in previously published reports. It is a non-scarring subtype of alopecia tha...
Source: Dermatology Online Journal - January 1, 2016 Category: Dermatology Source Type: research

Stem cell therapy as a novel therapeutic intervention for resistant cases of alopecia areata and androgenetic alopecia.
CONCLUSION: Autologous BMMCs and FSC seem to be a safe tolerable and effective treatment for the management of both resistant alopecia areata and androgenetic alopecia. PMID: 27553744 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - August 26, 2016 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Frictional alopecia of the distal legs: case series and review.
ConclusionThe incidence of acquired frictional alopecia of the lower extremities may be greater than reflected in previously published reports. It is a non-scarring subtype of alopecia that was noted as an incidental finding during the patient's dermatology appointment. PMID: 27617943 [PubMed - as supplied by publisher]
Source: Dermatol Online J - September 13, 2016 Category: Dermatology Authors: Zhao J, Cohen PR Tags: Dermatol Online J Source Type: research

Alopecia Areata is Associated with Increased Expression of Heart Disease Biomarker Cardiac Troponin I.
Abstract The development of androgenetic alopecia is associated with a risk of developing cardiovascular diseases, but the association of alopecia areata with cardiovascular diseases in humans is largely unexplored. We measured the plasma level of two common cardiovascular disease markers, cardiac troponin I and C-reactive protein, in alopecia areata and androgenetic alopecia affected subjects. Also, we investigated the possible presence of pro-apoptotic factors in the plasma of hair loss subjects. The mean plasma cardiac troponin I level was highest in alopecia areata subjects, moderately higher in androgenetic a...
Source: Acta Dermato-Venereologica - May 8, 2018 Category: Dermatology Authors: Wang EH, Santos L, Li XY, Tran A, Kim SSY, Woo K, Shapiro J, McElwee KJ Tags: Acta Derm Venereol Source Type: research

Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study
Conclusion: AGA followed by AA and TE were the most frequent cause of non-cicatricial alopecia, while FFA was the most frequent cause of cicatricial alopecia in all studied geographical areas.Skin Appendage Disord
Source: Skin Appendage Disorders - April 3, 2019 Category: Dermatology Source Type: research

Oxidative stress in androgenetic alopecia.
Discussions:Decreased total antioxidant activity and increased MDA levels found in plasma samples of patients with androgenetic alopecia are indicators of oxidative stress presence in these patients. Significantly decreased SOD activity but no change in catalase, glutathione peroxidase, non protein thiols level and total antioxidant activity in erythrocytes are elements which suggest the presence of a compensatory mechanism for SOD dysfunction in red blood cells of patients with androgenetic alopecia. ABBREVIATIONS: AAG = androgenetic alopecia, MDA = malondialdehyde, SOD = superoxide dismutase, CAT = catalase, GPx = gl...
Source: Journal of Medicine and Life - December 17, 2016 Category: Journals (General) Tags: J Med Life Source Type: research